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Rosebud BiosciencesGrowing micro-organs to find new drugs

Rosebud Biosciences accelerates drug development by screening drugs against organoids (micro-organs) that have the same gene mutations as the patients. We partner with therapeutics companies to screen their drugs, and we perform our own drug discovery for rare diseases that have no existing treatments. Our organoids are also fetal-like and enable discovery of novel drug targets for pediatric diseases. This technology was validated at Stanford, published in a prestigious journal, and has already led to the discovery of a drug target in a pediatric heart disease that could not have been found using traditional disease models.

2022-03-07
Active
Early
W22
3
Healthcare
United States of AmericaAmerica / CanadaRemotePartly Remote
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More About Rosebud Biosciences

Rosebud Biosciences: Discover Cures for Genetic Diseases

Revolutionizing Treatments for Children's Rare Genetic Diseases

Rosebud Biosciences is an early-stage startup dedicated to developing therapies for rare genetic diseases in children. By modeling human development with organoids that replicate the child's genetic mutations, we accelerate the search for effective cures.

Key Features

  • Organoid Platform: Utilizes disease-specific Human Induced Pluripotent Stem Cells (hiPSCs) for modeling genetic diseases.
  • Cardiac Organoids: Specialized in heart disease modeling.
  • Hepatic Organoids: Focused on liver disease modeling.
  • Neural Organoids: Targeting neural disease modeling.
  • Kidney Organoids: In progress for kidney disease modeling.
  • Longitudinal Surveillance: Continuous monitoring of organoid development from embryonic to differentiated tissue state.
  • High-Throughput Screening: Capable of monitoring up to 10,000 organoids simultaneously.

Use Cases

  • Drug Screening: Ideal for screening small molecules, RNA therapies (e.g., ASOs, siRNAs), CRISPR and other gene therapies, and immunotherapies.
  • Disease Modeling: Provides a scalable and human-relevant model for studying genetic diseases.
  • Pharma Partnerships: Collaborate with pharmaceutical companies to develop targeted therapies for heart, liver, neural, or kidney diseases.

Pricing

Rosebud Biosciences offers customized pricing based on the specific needs of your research or drug development project. Contact us for detailed pricing information tailored to your requirements.

Teams

Meet the Minds Behind Rosebud

  • CEO: Kitch Wilson, MD, PhD - A Stanford- and Duke-trained Physician-Scientist with over 16 years of experience in hiPSCs and genomic technologies.
  • CTO: Evan Lyall, PhD - A UC Berkeley-trained Scientist-Engineer with over 10 years of experience in advanced microscopy, data engineering, and machine learning.
  • Senior Scientist: Aditya Khedkar, MS - A Boston University- and Johns Hopkins-trained scientist with over 9 years of experience in gene editing and stem cell biology.

Rosebud Biosciences is actively seeking talented individuals to join our team. Explore job opportunities and become a part of our mission to find cures for rare genetic diseases.

Contact us to learn more about how Rosebud Biosciences can support your drug development efforts. Our team of experts is ready to assist you in achieving your research goals.